Anesthesia and Alzheimer's disease: time to wake up!

Anesthesia and Alzheimer's disease: time to wake up!

Apnea-hypopnea index: time to wake up

Despite the widespread use of the apnea-hypopnea index in research, its scientific and statistical properties have not been examined thoroughly. The index may be viewed either as a rate (number of events per hour of sleep) or as a ratio of two variables (number of events/number of hours of sleep). When considered as a rate, the apnea-hypopnea index may be modeled as the dependent variable, prov...

Wake-up to wake-up stroke!

is a typical story. a patient arrives at the emergency room. he was well when he went to bed and then he woke up with symptoms suggestive of stroke several hours later. even without further scrutiny, the clinician determines that intravenous thrombolytic therapy is contraindicated. end of story. Such is the plight of patients with wake-up stroke. Can we do more? Can we do better? Wake-up stroke...

Sleep and respiration in children: time to wake up!

The interest in paediatric sleep disorders over the last few decades has had its main focus on the sudden infant death syndrome (SIDS) - healthy infants who go to sleep and never wake up again. Overall, this is the most dramatic form of paediatric sleep disordered breathing. By contrast, classical presentations of sleep disordered breathing in children, such as snoring and obstructive sleep apn...

Time to wake up: reactive countermeasures to sleep inertia

Sleep inertia is the period of impaired performance and grogginess experienced after waking. This period of impairment is of concern to workers who are on-call, or nap during work hours, and need to perform safety-critical tasks soon after waking. While several studies have investigated the best sleep timing and length to minimise sleep inertia effects, few have focused on countermeasures -espe...